Synthesis and Stereochemical Assignment of (+)-Chamuvarinin
نویسندگان
چکیده
A stereocontrolled total synthesis of (+)-chamuvarinin, isolated from the root extract of Uvaria Chamae, utilizes a convergent modular strategy to construct the adjacently linked C15-C28 ether array, followed by a late-stage Julia-Kocienski olefination to append the butenolide motif. This constitutes the first total synthesis of (+)-chamuvarinin, defining the relative and absolute configuration of this unique annonaceous acetogenin.
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عنوان ژورنال:
دوره 13 شماره
صفحات -
تاریخ انتشار 2011